Thursday, October 30, 2014

New material advances tissue engineering, drug delivery

Researchers at the New York University Polytechnic School of Engineering have broken new ground in the development of proteins that form specialized fibers used in medicine and nanotechnology. For as long as scientists have been able to create new proteins that are capable of self-assembling into fibers, their work has taken place on the nanoscale. For the first time, this achievement has been realized on the microscale—a leap of magnitude in size that presents significant new opportunities for using engineered protein fibers.

Jin Kim Montclare, an associate professor of chemical and biomolecular engineering at the NYU School of Engineering, led a group of researchers who published the results of successful trials in the creation of engineered microfiber proteins in the journal Biomacromolecules.

Many materials used in medicine and nanotechnology rely on proteins engineered to form fibers with specific properties. For example, the scaffolds used in tissue engineering depend on engineered fibers, as do the nanowires used in biosensors. These fibers can also be bound with small molecules of therapeutic compounds and used in drug delivery.

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